Searchable abstracts of presentations at key conferences in endocrinology

ea0081rc10.7 | Rapid Communications 10: Diabetes, Obesity, Metabolism and Nutrition 3 | ECE2022

Knowledge about Diabetic Ketoacidosis in Patients with Type 1 Diabetes mellitus – Data of a Patient-centered Questionnaire

Hepprich Matthias , Stiebitz Sebastian , Schultes Bernd , Schmitz Daniela , Felix Barbara , Rutishauser Jonas , Schubert Sabine , Roser Pia , Aberle Jens , Rudofsky Gottfried

Background/Introduction: Diabetic ketoacidosis (DKA) is a severe complication of diabetes mellitus type 1 (T1DM) with potentially life-threatening course. Data on patient knowledge about DKA in German-speaking countries is rare. Thus, we aimed to gather data about T1DM patients’ knowledge in terms of DKA.Methods: Together with two T1DM patients and an experienced diabetes counselor, we developed an anonymous questionnaire covering general knowledge ...

ea0063gp137 | Obesity | ECE2019

Empagliflozin as well as Anakinra reduce symptomatic hypoglycemia in patients after Roux-Y-gastric bypass by lowered insulin secretion

Hepprich Matthias , Wiedemann Sophia , Schelker Benjamin , Starkle Alessandra , Trinh Beckey , Boni-Schnetzler Marianne , Rudofsky Gottfried , Donath Marc

Background: Postprandial hypoglycemia is an increasingly recognized complication after bariatric surgery. Its hallmark is a pronounced glycemic rise after carbohydrate ingestion followed by an exaggerated hyperinsulinemic response. Recent studies have shown that IL-1β contributes to postprandial stimulation of insulin. Furthermore, inhibition of SGLT2 reduces excessive plasma glucose increase. Therefore, we investigated whether inhibition of IL-1β with the IL-1 recep...